At e184, we are looking for talented, passionate people ready to build technology for the goals that matter most. In labs around the world, we are working to enable reproductive rights for all with projects in in vitro gametogenesis and artificial wombs, and building brain-computer interfaces for fluid collaboration between humans and AI. 

Our technology can give everyone a say in what the future holds in store.

What you’ll do

At e184, we are building systems that fundamentally accelerate scientific discovery across multiple scientific domains including genomics, neuroscience, and developmental biology, and emerging interdisciplinary fields. As a CTO, you will wake up every day thinking about how to turn complex, fragmented scientific processes into intelligent, automated, and trustworthy workflows.

You will immerse yourself in how our science actually happens - from wet and dry lab operations to imaging pipelines and experimental data flows. By working directly with researchers, you’ll identify high-impact opportunities where AI, automation, and robotics can eliminate repetitive work in areas such as sample processing, imaging, cell culture screening, and experimental execution - freeing scientists to focus on discovery rather than operations.

From there, you’ll design and implement orchestrated, end-to-end workflows that connect laboratory devices, APIs, datasets, and AI models into coherent systems. Monitoring, traceability, and reliability won’t be afterthoughts - they’ll be built in from day one, ensuring every decision can be understood, trusted, and reproduced.A core part of your work will be blending large language models and other advanced architectures with live scientific data, enabling systems that reason with real context, adapt in real time, and support better decisions exactly when they’re needed. You’ll help establish a unified foundation for data standards, metadata schemas, experiment tracking, versioning, access control, audit trails, and security - so AI operates on solid ground.

You’ll stay hands-on, building conversational agents and intelligent bots that do more than answer questions. These systems will take actions, understand nuance, and actively assist scientific teams in their daily work. Some will live on the web, others will integrate into tools and environments we haven’t even adopted yet - and you’ll help define that roadmap.

Throughout all of this, you’ll collaborate closely with scientists, engineers, and operators across the company translating complex research needs into AI-powered systems that respect governance, build trust in data, and deliver measurable impact. Your work will directly enable teams at e184 to move faster, work smarter, and unlock breakthroughs that would otherwise take years to reach.

Core requirements

• Bachelor’s or Master’s degree in Computer Science, Engineering, or related field.
• 3+ years of hands-on experience building and deploying AI/ML systems or infrastructure in research-critical environments.
• Strong experience using LangChain/LangGraph for building LLM applications.
• Deep knowledge of vector databases (FAISS, PGVector, Qdrant) and RAG architectures for scientific knowledge retrieval and question-answering systems.
• Proficiency in Python, FastAPI, and key ML frameworks (Transformers, PyTorch, TensorFlow).
• Proven ability in advanced prompt engineering techniques.
• Hands-on approach and experience setting up integration of multiple solutions from scratch. You build systems yourself, end-to-end. You write the code, train the models, deploy the systems, and keep them running.

You´ll stand out with

• Experience with supporting new processes, products, operations, labs, manufacturing sites, etc.
• Prior experience supporting life sciences research teams or building research infrastructure.
• Familiarity with omics and single-cell data, neural time series and neuroimaging.
• Computer vision experience, especially for microscopy, medical imaging, or scientific image analysis.
• Familiarity with n8n or similar workflow orchestration platforms.
• Experience deploying and managing production-scale LLMs (AWS SageMaker, Azure ML, Hugging Face).
• Practical fine-tuning skills (LoRA, full-model fine-tuning, hyperparameter optimization).
• Experience with containerization (Docker) and orchestration systems (Kubernetes).
• Solid understanding of MLOps and LLMOps tools and practices (MLFlow, Grafana, Prometheus).

Why e184?

• Remote role with trips to the labs.
• Competitive compensation.
• Collaborative and supportive culture with mission-driven colleagues.

Guy’s and St Thomas’ is among the UK’s busiest and most successful NHS foundation trusts. We provide a full range of hospital and community services for people in south London and as well as specialist care for patients from further afield including cancer, renal, orthopaedic, respiratory and cardiovascular services.

Guy’s is home to the largest dental school in Europe and a £160 million Cancer Centre opened in 2016. As part of our commitment to provide care closer to home, in 2017 we also opened a cancer centre and a kidney treatment centre at Queen Mary’s Hospital in Sidcup. St Thomas’ has one of the largest critical care units in the UK and one of the busiest emergency departments in London. It is also home to Evelina London Children’s Hospital.

Evelina London cares for local children in Lambeth and Southwark and provides specialist services across south east England including cardiac, renal and critical care services. We lead a number of specialist service networks aiming to ensure children are treated locally where possible, but have access to specialist expertise when they need it. Our community services include health visiting, school nursing and support for families of children with long-term conditions. 

Our adult community services teams deliver care at the heart of the local communities we serve, working in partnership with GPs, local authorities and other healthcare and voluntary sector organisations. Working with our partners in Lambeth and Southwark, we are focusing on new ways of working to improve care for local patients.

In February 2021 the Royal Brompton and Harefield joined Guy’s and St Thomas’ NHS Foundation Trust, bringing together world-leading expertise in the care and research of heart and lung disease. Our merger provides a once in a generation opportunity to build a lasting, world-renowned heart and lung centre, providing the highest quality care for patients and conducting world-leading research.

We have a reputation for clinical excellence and high quality teaching and research. We are part of King’s Health Partners, one of eight accredited UK academic health sciences centres. In partnership with King’s College London we have dedicated clinical research facilities including an MHRA accredited Phase I clinical trials unit.

Patients are at the heart of everything we do and we pride ourselves on ensuring the best possible patient experience as well as safe, high quality care. We are proud to have one of the lowest mortality rates in the NHS. Following a comprehensive Care Quality Commission (CQC) inspection in 2019 we maintained our overall rating of ‘good’. Our adult community services achieved a rating of ‘outstanding’.

The commitment of our 23,500 staff is key to our success. We are one of the largest local employers and we aim to develop and support all our staff so they are able to deliver high quality, safe and efficient care. The 2019 NHS staff survey results show that we have one of the most engaged and motivated workforces in the NHS. We know this has a positive impact on the care provided to our patients.

We have one of the most ambitious capital investment programmes anywhere in the NHS.

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Job overview

The Integrated & Specialist Medicine (ISM) Clinical Group is seeking an innovative, collaborative and highly skilled Head of Business Intelligence to lead our analytics capability and drive data‑enabled improvement across eight diverse directorates.

We are looking for a compassionate, motivated and forward‑thinking leader who can bring strategic insight, technical credibility and positive energy to this pivotal role. You will lead our established Engine Room analytics function and play a central role in shaping how the Clinical Group uses data to drive clinical excellence, operational performance and improvement. This is an exciting moment to join ISM, with expanding digital capabilities, increasing demand for actionable analytics and a growing portfolio of transformation priorities. The successful candidate will have significant opportunities to influence decision‑making, develop new analytical approaches and build a high‑performing analytics culture. If you are a leader who thrives on impact, innovation and improving patient outcomes, we would be delighted to hear from you.

Main duties of the job

The Head of Business Intelligence is accountable to the Director of Operations & Partnerships and works closely with the Clinical Group CEO, Executive Team and senior clinical leads. Your responsibilities include:

• Providing strategic and operational leadership for all analytics and reporting activity across ISM.
• Leading and developing the Business Intelligence and Engine Room Clinical Analytics teams.
• Overseeing statutory national submissions and ensuring the accuracy, completeness and timeliness of ISM data.
• Translating complex data into meaningful insight to support service improvement, business planning and clinical governance.
• Advising senior leaders on analytical methodologies, performance trends and the impact of change.
• Driving forward innovation in predictive analytics, dashboarding and data quality.
• Representing the Clinical Group in trust‑wide digital programmes, including EHR development and data governance.

The ideal candidate will bring strong analytical leadership, confident communication skills and the ability to work effectively within a complex, multi‑professional environment.

Working for our organisation

The ISM Clinical Group is one of four Clinical Groups at Guy’s and St Thomas’ and includes services such as Acute & General Medicine, Specialist Ambulatory & Medical Specialties, Clinical Imaging & Medical Physics, Pharmacy, Dental and Integrated & Local Services. You will work closely with a supportive Executive Team comprising the CEO, Medical Director, Director of Nursing, People Director, Head of Finance and Directors of Operations & Partnership.

Our values guide everything we do:

Caring, Inclusive and Ambitious.
We encourage applicants from all backgrounds and are committed to equality, diversity and inclusion across our workforce.

At 3HORIZONS, we’re reshaping what strategy means in the real world - not as a document, but as a force for impact. We are a global strategy consultancy trusted by leading organisations across industries: from multi-billion industrial powerhouses and pharmaceutical giants to cutting-edge manufacturers and even Super Bowl champions. Our mission is simple: help leadership teams close the gap between ambition and execution - faster, smarter, and more effectively than traditional consulting ever could.The engine behind this transformation is the Strategy in Action System:

• Enterprise-grade software that turns strategy into live, structured workflows
• An AI intelligence engine that surfaces real-time insights, risks and opportunities
• Certified experts who bring pace, challenge and alignment into every leadership room

Founded in 2005 and headquartered in London, with offices in New York, Turin and Nicosia, we bring together strategy consultants, industry experts and product innovators to deliver strategy with clarity, momentum and measurable results.
We don’t just advise - we co-create strategy and build strategic capability inside organisations, empowering teams long after the engagement ends. 3HORIZONS has been certified as a Great Place to Work® for 3 consecutive years.

Job Description

• Independently manage end-to-end project executions and lead a team of employees (up to 3 people on a project) who conduct structured analyses and primary research to gain new insights that inform your client recommendations.
• Serve as a point of contact for clients and identify opportunities for client relationship building and development.
• Foster a high-performance culture within the team by overseeing the day-to-day execution of client projects and guiding the individual development of junior colleagues.
• Lead workshops with various target audiences and present the most practical way to achieve lasting results based on your insights at team and client meetings.
• Work in complex, highly dynamic contexts as a project manager and also provide operational support by structuring analyses.
• With the entire Strategy in Action team, you actively contribute your own ideas to the development of the company, participating in the advancement of our technologies, methods, and consulting approaches.

Qualifications

• +3 years of professional experience at a top tier strategy consulting firm or strategy experience in a reputed organisation
• Master's degree from a top university with an outstanding academic record (technical background is an advantage); an advanced degree or MBA is preferred
• Proven track record of high performance and significant achievements in your previous roles.
• Demonstrated ability to successfully influence partners and executives
  Mindset & Characteristics:
• Entrepreneurial mindset, knowledge, and application of Lean Testing, MVPs,disciplined experimentation, etc.
• Exceptional analytical and quantitative problem-solving skills
• Demonstrated leadership skills in a team environment
• Customer-oriented, strong interpersonal skills to independently manage clients and teams
• Initiative-taker, willing to explore new paths and create opportunities for others
• Fluent in English
• Availability for international travel
  
  Desirable:
   
• Knowledge of French/German and /or Italian is advantageous

We are seeking a highly motivated and analytical individual to join our team as a Finance & Strategy Senior Manager. They will play a key role in financial and strategic planning, analysis and decision-making within the organisation. You will need to be able to understand the big picture, while also being unafraid to dive into the details and numbers. 

What you'll do

• Partner with business leaders helping them to make better strategic decisions by enabling them through data and understanding of financial trade-offs
• Create, update and maintain financial models, budgets and forecasts
• Build out business reporting metrics and dashboards to support decision-making
• Perform analysis of financial and operational drivers to craft our short and long-term strategic plan
• Analyse market trends, competitive landscape and industry benchmarks to assess market opportunities
• Lead and engage on cross-functional strategic projects

Experience and skills

• A degree in Business, Strategy, Finance, Math, Statistics, Economics, Accounting or other quantitative discipline
• 6+ years experience in investment banking, consulting or in finance at a high growth company
• Technology industry experience in FP&A or strategic finance a plus
• Strong analytical and creative problem-solving skills, with strong modeling experience
• Ability to work autonomously
• Ability to influence proceedings in a fast moving organisation
• Enthusiasm and curiosity for conducting research and answering hard questions with data

What's in it for you?

• Opportunity to join a fast-growing, award-winning and super ambitious company.
• Work with a friendly team of highly motivated individuals.
• Be in an environment where you are listened to and can actually have an impact.
• Thriving collaborative and inclusive company culture.
• Competitive remuneration package.
• Company pension scheme
• Hybrid working environment
• Home office furniture allowance
• Personal Annual Learning and Development budget
• Private Medical Insurance
• Health Cash Plan (cashback on visits to the dentist & opticians etc)
• Cycle to work scheme
• Gympass subscription to a variety of gyms and wellbeing apps
• Enhanced parental pay & leave
• 25 days holiday + bank holidays with additional days added with length of service.
• This is a hybrid role. Our office is in London, by the Oxo Tower
• #LI-CS1